Young Adult Exposure to Cardiovascular Risk Factors and Risk of Events Later in Life: The Framingham Offspring Study
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Current versionv1pletcher-framingham-offspring-study-2016.pdf
Approvals1/5Version-specific
Open changes21 closed
Document verificationCaptured
Technical details
SHA-256: c3f71f1ab0bb9e029a01de923e251939e43e6e21dbfcd9e159857f97f6dbf7afPeople and decisions
5 peopleMara Chenmara.chen@example.orgEditor
Trajectory-methods wording needs lead review.
Dr. Michael Abramsmichael.abrams@example.orgReviewer
Approved citation, license, and data-source note
Dr. Helen Carterhelen.carter@example.orgReviewer
Requested DBP/LDL-only wording
Dr. Jonah Leejonah.lee@example.orgReviewer
Commented on Table 3 hazard ratios
Dr. Elaine Rosselaine.ross@example.orgReviewer
Requested trajectory-modeling clarification
Comments and change requests
4 totalDr. Helen CarterPlease keep the approval summary specific: early-adult DBP and LDL remained independently associated after adjustment; SBP and HDL did not.Abstract results
Open change
Dr. Michael AbramsCitation and license look acceptable. Please keep the PLOS DOI, CC BY attribution, and BioLINCC data-availability context in the export record.Citation and license
Resolved
Dr. Elaine RossThe methods note should explain that young-adult exposure was estimated from mixed-model trajectories, not directly observed for every participant at ages 20-39.Trajectory modeling methods
Open change
Dr. Jonah LeeTable 3 is the right place to anchor the adjusted hazard-ratio discussion: DBP >90 and LDL >160 have the strongest adjusted estimates.Table 3
Comment